DCA

Graph-Guided Deep Embedding Clustering for Brain Atlases

Mo Wang, Kaining Peng, Jingsheng Tang, Hongkai Wen, Quanying Liu
Southern University of Science and Technology · University of Warwick

NeurIPS 2025 · official proceedings available

NeurIPS 2025DCA framework: group pretraining and graph-guided personalized atlas generation
Original paper · Figure 2 View full figure ↗
At a glance

What this study adds

Summary of the linked study; findings refer to that study’s own comparisons.

Question
Can brain atlases adapt to individual functional organization?
Approach
Combine pretrained voxel embeddings with spatially guided clustering.
Evidence
Atlas construction on HCP, downstream evaluation on HCP/ABIDE/ADNI, and transfer assessment on CHCP.
Finding
The NeurIPS paper reports improved functional homogeneity, clustering quality, and downstream utility against its compared atlases.

Source and scope

This fMRI Atlas page is a curated research summary, not the original study. The question, method, evidence and finding above summarize the authors’ report; results have not been independently reproduced here. See the original paper for methods, authorship and full results.

Evidence boundary: Atlas quality and downstream utility are reported for the evaluated cohorts and baselines; clinical use is not established by this directory entry.

Page reviewed: .

Overview

DCA constructs brain atlases at voxel resolution, using fMRI features to tailor parcels to individual subjects. A pretrained autoencoder supplies the embeddings, while a spatial graph guides clustering so that each parcel stays connected. Users can choose the number of parcels and the brain region to partition. The work also introduces AtlaScore, a benchmark for comparing atlas quality and downstream utility.

Summary of the original paper, revised September 20, 2025 (v2).

Method

Masked fMRI reconstruction pretrains a Swin-UNETR encoder. Its voxel embeddings define soft cluster assignments and edge weights on a local spatial graph. Spectral clustering supplies targets that refine the assignments and learnable centroids.

Original Figure 2 from the DCA paper
Figure 2 · Wang et al., 2025. Original paper. Figure reproduced without modification; credit to the paper authors.

BibTeX

@inproceedings{wang2025dca,
  title={DCA: Graph-Guided Deep Embedding Clustering for Brain Atlases},
  author={Wang, Mo and Peng, Kaining and Tang, Jingsheng and Wen, Hongkai and Liu, Quanying},
  year={2025},
  booktitle={Advances in Neural Information Processing Systems},
  volume={38},
  doi={10.52202/085713-3450},
  url={https://papers.nips.cc/paper_files/paper/2025/hash/954729c2c57c32cab97c4f868dbb4d3e-Abstract-Conference.html}
}
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